49ers vs. Falcons Odds, Spreads, and Lines
The San Francisco 49ers and Atlanta Falcons will go to head-to-head in this NFL Week 7 game on Sunday afternoon. The game will kick-off at 1:00 p.m. ET, and will be played at Mercedes-Benz Stadium in Atlanta.
Below, you'll find the latest 49ers vs. Falcons odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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49ers vs. Falcons Matchup Information
Date: Sunday, Oct. 25, 2026
Time: 1:00 p.m. ET
Location: Mercedes-Benz Stadium, Atlanta, GA
TV: FOX
49ers vs. Falcons Odds
San Francisco is the -200 moneyline favorite against the Falcons at Fanatics Sportsbook, with Atlanta +165 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
49ers vs. Falcons Moneyline Odds
- 49ers Moneyline -200
- Falcons Moneyline +165
The above odds are correct at the time of writing, see below for live odds
49ers vs. Falcons Spread Odds
- 49ers -3.5 -110
- Falcons +3.5 -110
- 49ers -8.5 +190
- Falcons +8.5 -250
- 49ers +1.5 -235
- Falcons -1.5 +180
49ers vs. Falcons Over/Under Odds
- Over 49.5 -110
- Under 49.5 -110
- Over 54.5 +160
- Under 54.5 -205
- Over 44.5 -205
- Under 44.5 +160
49ers vs. Falcons Player Prop Odds
Bijan Robinson is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -240. Christian McCaffrey and George Kittle are next on the board. See the latest Brock Purdy odds and Tua Tagovailoa odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the 49ers vs. Falcons game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
49ers vs. Falcons Anytime Touchdown Scorer Odds
- Bijan Robinson -240
- Christian McCaffrey -205
- George Kittle -105
- Brian Robinson +175
- Drake London +210
49ers vs. Falcons +EV Bets
Below are the highest positive expected value bets for the 49ers vs. Falcons game at Fanatics Sportsbook:
- San Francisco 49ers -4.5 Spread +105 (EV 9.96%)
- Under 51.5 Total Points -125 (EV 9.55%)
- San Francisco 49ers -5.5 Spread +115 (EV 9.5%)
49ers vs. Falcons Odds FAQs
What are the latest odds for 49ers vs. Falcons?
The 49ers are moneyline favorites at -200, the Falcons are moneyline outsiders at +165. The point spread line is set at 3.5, with the over/under total line at 49.5 at Fanatics Sportsbook.
Who is favored to win 49ers vs. Falcons?
The 49ers are favored to win against the Falcons with moneyline odds of -200, which implies a 66.67% win probability.
What is the point spread for 49ers vs. Falcons?
The point spread for the 49ers vs. Falcons is 3.5 at Fanatics Sportsbook, with San Francisco at -3.5 and Atlanta at +3.5.
What is the over/under for 49ers vs. Falcons?
The over/under line for the 49ers vs. Falcons at Fanatics Sportsbook is 49.5.
Where can I find the latest 49ers vs. Falcons betting lines?
You can find the latest betting lines for 49ers vs. Falcons at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.