Chargers vs. Rams Odds, Spreads, and Lines

The Los Angeles Chargers and Los Angeles Rams will go to head-to-head in this NFL Week 8 game on Sunday afternoon. The game will kick-off at 4:05 p.m. ET, and will be played at SoFi Stadium.
Below, you'll find the latest Chargers vs. Rams odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
New to Fanatics Sportsbook? The Fanatics Sportsbook promo code is FAN350. New customers who sign up with code FAN350 get $350 in FanCash after they wager $20 or more at odds of ‑500 or longer within your first 7 days. Available to new users 21+.
Chargers vs. Rams Matchup Information
Date: Sunday, Nov. 1, 2026
Time: 4:05 p.m. ET
Location: SoFi Stadium, Inglewood, CA
TV: CBS
Chargers vs. Rams Odds
The Rams are -300 moneyline favorites at Fanatics Sportsbook, with the Chargers +240 underdogs. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Chargers vs. Rams Moneyline Odds
- Chargers Moneyline +240
- Rams Moneyline -300
The above odds are correct at the time of writing, see below for live odds
Chargers vs. Rams Spread Odds
- Rams -6.5 -110
- Chargers +6.5 -110
- Rams -11.5 +185
- Chargers +11.5 -240
- Rams -1.5 -265
- Chargers +1.5 +200
Chargers vs. Rams Over/Under Odds
- Over 45 -110
- Under 45 -110
- Over 50.5 +160
- Under 50.5 -205
- Over 40.5 -190
- Under 40.5 +150
Chargers vs. Rams Player Prop Odds
Puka Nacua and Kyren Williams are the most likely scorers in the anytime touchdown market at Fanatics Sportsbook, at odds of -165. Blake Corum is next on the board. See the latest Justin Herbert odds and Matthew Stafford odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Chargers vs. Rams game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Chargers vs. Rams Anytime Touchdown Scorer Odds
- Puka Nacua -165
- Kyren Williams -165
- Blake Corum +130
- Ladd McConkey +190
- Omarion Hampton +210
Chargers vs. Rams +EV Bets
Below are the highest positive expected value bets for the Chargers vs. Rams game at Fanatics Sportsbook:
- Kyren Williams Anytime Touchdown Scorer -165 (EV 14.45%)
- Omarion Hampton Anytime Touchdown Scorer +210 (EV 12.13%)
- Blake Corum Anytime Touchdown Scorer +130 (EV 3.43%)
Chargers vs. Rams Odds FAQs
What are the latest odds for Chargers vs. Rams?
The Rams are the -300 moneyline favorite Fanatics Sportsbook, with the Chargers +240 outsiders. The point spread line is set at 6.5, with the over/under total line at 45 at Fanatics Sportsbook.
Who is favored to win Chargers vs. Rams?
The Rams are -300 favorites on the moneyline, which is a 75% win probability.
What is the point spread for Chargers vs. Rams?
The point spread for the Chargers vs. Rams is 6.5 at Fanatics Sportsbook, with the Rams -6.5 and the Chargers at +6.5.
What is the over/under for Chargers vs. Rams?
The over/under line for the Chargers vs. Rams at Fanatics Sportsbook is 45.
Where can I find the latest Chargers vs. Rams betting lines?
You can find the latest betting lines for Chargers vs. Rams at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.