Jaguars vs. Broncos Odds, Spreads, and Lines

The Jacksonville Jaguars and Denver Broncos go to head-to-head in this NFL Week 2 game on Sunday afternoon. The game will kick-off at 4:05 p.m. ET, and will be played at the Empower Field at Mile High in Denver.
Below, you'll find the latest Jaguars vs. Broncos odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Jaguars vs. Broncos Matchup Information
Date: Sunday, Sept. 20, 2026
Time: 4:05 p.m. ET
Location: Empower Field at Mile High, Denver, CO
TV: CBS
Jaguars vs. Broncos Odds
Denver is the -150 moneyline favorite against the Jaguars at Fanatics Sportsbook, with Jacksonville +120 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the Week 2 game.
Jaguars vs. Broncos Moneyline Odds
- Broncos Moneyline -150
- Jaguars Moneyline +125
The above odds are correct at the time of writing, see below for live odds
Jaguars vs. Broncos Spread Odds
- Jaguars +3 -115
- Broncos -3 -105
- Jaguars +6.5 -210
- Broncos -6.5 +165
- Jaguars -0.5 +125
- Broncos +0.5 -155
Jaguars vs. Broncos Over/Under Odds
- Over 45.5 -110
- Under 45.5-110
- Over 41.5 -170
- Under 41.5 +135
- Over 49.5 +145
- Under 49.5 -180
Jaguars vs. Broncos Player Prop Odds
J.K. Dobbins is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of +135. Bhayshul Tuten and Parker Washington are next on the board. See the latest Bo Nix odds and Trevor Lawrence odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for Jaguars vs. Broncos, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Jaguars vs. Broncos Anytime Touchdown Scorer Odds
- J.K Dobbins +135
- Bhayshul Tuten +150
- Parker Washington +190
- RJ Harvey +210
- Jaylen Waddle +225
- Courtland Sutton +240
Jaguars vs. Broncos Betting Trends
Below are live betting odds from Fanatics Sportsbook, as well as hit rate data and trends across recent games:
- Jacksonville Jaguars have won 9 of their last 10 games.
- Trevor Lawrence has exceeded 220.5 passing yards in 8 of their last 10 games.
- J.K. Dobbins has exceeded 55.5 rushing yards in 8 of their last 10 games.
- J.K. Dobbins has exceeded 50.5 rushing yards in 8 of their last 10 games.
- Parker Washington has exceeded 50.5 receiving yards in 7 of their last 10 games.
Jaguars vs. Broncos FAQs
What are the latest odds for Jaguars vs. Broncos?
The Broncos are moneyline favorites at -150, the Jaguars are moneyline outsiders at +125. The point spread line is set at 3, with the over/under total line at 45.5 at Fanatics Sportsbook.
Who is favored to win Jaguars vs. Broncos?
The Broncos are favored to win against the Jaguars with moneyline odds of -150, which implies a 60% win probability.
What is the point spread for Jaguars vs. Broncos?
The point spread for the Jaguars vs. Broncos is 3 at Fanatics Sportsbook, with Jacksonville at +3 and Denver at -3.
What is the over/under for Jaguars vs. Broncos?
The over/under line for Jaguars vs. Broncos at Fanatics Sportsbook is 45.5.
Where can I find the latest Jaguars vs. Broncos betting lines?
You can find the latest betting lines for Jaguars vs. Broncos at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.