Saints vs. Lions Odds, Spreads, and Lines
The Detroit Lions and New Orleans Saints to head-to-head in this NFL Week 1 game on Sunday afternoon. The game will kick-off at 1:00 p.m. ET, and will be played at Ford Field, Detroit.
Below, you'll find the latest Lions vs. Saints odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Saints vs. Lions Matchup Information
Date: Sunday, Sept. 13, 2026
Time: 1:00 p.m. ET
Location: Ford Field, Detroit, MI
TV: FOX
Saints vs. Lions Odds
Detroit is the -330 moneyline favorite against the Saints at Fanatics Sportsbook, with New Orleans +260 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the Week 1 game.
Saints vs. Lions Moneyline Odds
- Lions Moneyline -330
- Saints Moneyline +260
The above odds are correct at the time of writing, see below for live odds
Saints vs. Lions Spread Odds
- Saints +7 -110
- Lions -7 -110
- Saints +10 -175
- Lions -10 +140
- Saints +4 +145
- Lions -4 -180
Saints vs. Lions Over/Under Odds
- Over 50 -110
- Under 50 -110
- Over 47.5 -135
- Under 47.5 +110
- Over 53.5 +130
- Under 53.5 -160
Saints vs. Lions Player Prop Odds
Jahmyr Gibbs is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -260. Travies Etienne and Amon-Ra St. Brown are next on the board. Jared Goff is priced at -110 to go over 260.5 passing yards, with Tyler Shough at -110 for over 245.5 passing yards.
Fanatics Sportsbook is offering a range of additional player prop markets for Lions vs. Saints, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Saints vs. Lions Anytime Touchdown Scorer Odds
- Jahmyr Givvs -260
- Travis Etienne -120
- Amon-Ra St. Brown +100
- Chris Olave +120
- Jameson Williams +180
- Sam LaPorta +190
- Jacob Saylors +300
Saints vs. Lions Betting Trends
Below are live betting odds for Lions vs. Saints at Fanatics Sportsbook, as well as hit rate data and trends across recent games:
- Jared Goff has exceeded 255.5 passing yards in 8 of their last 10 games.
- Jared Goff has exceeded 32.5 passing attempts in 8 of their last 10 games.
- Jahmyr Gibbs has failed to exceed 18.5 rushing attempts in 8 of their last 10 games.
- Jahmyr Gibbs has failed to exceed 80.5 rushing yards in 8 of their last 10 games.
- Jahmyr Gibbs has failed to exceed 85.5 rushing yards in 8 of their last 10 games.
Saints vs. Lions FAQs
What are the latest odds for Saints vs. Lions?
The Lions are moneyline favorites at -330, the Saints are moneyline outsiders at +260. The point spread line is set at 7, with the over/under total line at 50 at Fanatics Sportsbook.
Who is favored to win Saints vs. Lions?
The Lions are favored to win against the Saints with moneyline odds of -330, which implies a 76.70% win probability.
What is the point spread for Saints vs. Lions?
The point spread for the Lions vs. Saints is 7 at Fanatics Sportsbook, with New Orleans at +7 and Detroit at -7.
What is the over/under for Saints vs. Lions?
The over/under line for Lions vs. Saints at Fanatics Sportsbook is 50.
Where can I find the latest Saints vs. Lions betting lines?
You can find the latest betting lines for Lions vs. Saints at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.