Seahawks vs. Cardinals Odds, Spreads, and Lines
The Seattle Seahawks and Arizona Cardinals go to head-to-head in this NFL Week 2 game on Sunday afternoon. The game will kick-off at 4:25 p.m. ET, and will be played at the State Farm Stadium in Glendale.
Below, you'll find the latest Seahawks vs. Cardinals odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Seahawks vs. Cardinals Matchup Information
Date: Sunday, Sept. 20, 2026
Time: 4:25 p.m. ET
Location: State Farm Stadium, Glendale, AZ
TV: FOX
Seahawks vs. Cardinals Odds
Seattle is the -205 moneyline favorite against the Cardinals at Fanatics Sportsbook, with Arizona +170 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the Week 2 game.
Seahawks vs. Cardinals Moneyline Odds
- Seahawks Moneyline -205
- Cardinals Moneyline +170
The above odds are correct at the time of writing, see below for live odds
Seahawks vs. Cardinals Spread Odds
- Cardinals +3.5 -105
- Seahawks -3.5 -115
- Cardinals +7.5 -210
- Seahawks -7.5 +165
- Cardinals -0.5 +165
- Seahawks +0.5 -210
Seahawks vs. Cardinals Over/Under Odds
- Over 41 -110
- Under 41 -110
- Over 36.5 -190
- Under 36.5 +150
- Over 45.5 +140
- Under 45.5 -175
Seahawks vs. Cardinals Player Prop Odds
Jaxon Smith-Njigba is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of +140. Jadarian Price and Jeremiyah Love are next on the board. See the latest Sam Darnold odds and Jacoby Brissett odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for Seahawks vs. Cardinals, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Seahawks vs. Cardinals Anytime Touchdown Scorer Odds
- Jaxon Smith-Njigba +140
- Jadarian Price +160
- Jeremiyah Love +200
- George Holani +200
- Trey McBride +220
- Tyler Allgeier +230
Seahawks vs. Cardinals Betting Trends
Below are live betting odds from Fanatics Sportsbook, as well as hit rate data and trends across recent games:
- Seattle Seahawks have won 10 of their last 10 games.
- Michael Wilson has exceeded 35.5 receiving yards in 9 of their last 10 games.
- Jacoby Brissett has exceeded 210.5 passing yards in 9 of their last 10 games.
- Michael Wilson has exceeded 40.5 receiving yards in 8 of their last 10 games.
- Jacoby Brissett has exceeded 215.5 passing yards in 8 of their last 10 games.
Seahawks vs. Cardinals FAQs
What are the latest odds for Seahawks vs. Cardinals?
The Seahawks are moneyline favorites at -205, the Cardinals are moneyline outsiders at +170. The point spread line is set at 3.5, with the over/under total line at 41 at Fanatics Sportsbook.
Who is favored to win Seahawks vs. Cardinals?
The Seahawks are favored to win against the Cardinals with moneyline odds of -205, which implies a 67.2% win probability.
What is the point spread for Seahawks vs. Cardinals?
The point spread for the Seahawks vs. Cardinals is 3.5 at Fanatics Sportsbook, with Arizona at +3.5 and Seattle at -3.5.
What is the over/under for Seahawks vs. Cardinals?
The over/under line for Seahawks vs. Cardinals at Fanatics Sportsbook is 41.
Where can I find the latest Seahawks vs. Cardinals betting lines?
You can find the latest betting lines for Seahawks vs. Cardinals at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.