Cardinals vs. Giants Odds, Spreads, and Lines
The Arizona Cardinals and New York Giants will go to head-to-head in this NFL Week 4 game on Sunday afternoon. The game will kick-off at 1:00 p.m. ET, and will be played at the MetLife Stadium.
Below, you'll find the latest Cardinals vs. Giants odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Cardinals vs. Giants Matchup Information
Date: Sunday, Oct. 4, 2026
Time: 1:00 p.m. ET
Location: MetLife Stadium, East Rutherford, NJ
TV: CBS
Cardinals vs. Giants Odds
Arizona is the -120 moneyline favorite against the Giants at Fanatics Sportsbook, with New York +100 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Cardinals vs. Giants Moneyline Odds
- Cardinals Moneyline -120
- Giants Moneyline +100
The above odds are correct at the time of writing, see below for live odds
Cardinals vs. Giants Spread Odds
- Giants +1 -110
- Cardinals -1 -110
- Giants +5.5 -265
- Cardinals -5.5 +200
- Giants -3.5 +170
- Cardinals +3.5 -220
Cardinals vs. Giants Over/Under Odds
- Over 44.5 -110
- Under 44.5 -110
- Over 39.5 -195
- Under 39.5 +155
- Over 59.5 +160
- Under 59.5 -205
Cardinals vs. Giants Player Prop Odds
Cameron Skattebo is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -135. Jeremiyah Love and Malik Nabers are next on the board. See the latest Jacoby Brissett odds and Jaxson Dart odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Cardinals vs. Giants game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Cardinals vs. Giants Anytime Touchdown Scorer Odds
- Cameron Skattebo -135
- Jeremiyah Love +100
- Malik Nabers +175
- Isaiah Likely +190
- Trey McBride +195
Cardinals vs. Giants +EV Bets
Below are the highest positive expected value bets for the Cardinals vs. Giants game at Fanatics Sportsbook:
- Trey McBride Anytime Touchdown Scorer (EV 49.18%)
- Under 46 Total Points (EV 8.72%)
- Under 46.5 Total Points (EV 8.12%)
- Under 45.5 Total Points (EV 7.56%)
- Under 45 Total Points (EV 6.42%)
Cardinals vs. Giants Odds FAQs
What are the latest odds for Cardinals vs. Giants?
The Cardinals are moneyline favorites at -120, the Giants are moneyline outsiders at +100. The point spread line is set at 1, with the over/under total line at 44.5 at Fanatics Sportsbook.
Who is favored to win Cardinals vs. Giants?
The Cardinals are favored to win against the Giants with moneyline odds of -120, which implies a 54.5% win probability.
What is the point spread for Cardinals vs. Giants?
The point spread for the Cardinals vs. Giants is 1 at Fanatics Sportsbook, with New York at +1 and Arizona at -1.
What is the over/under for Cardinals vs. Giants?
The over/under line for the Cardinals vs. Giants at Fanatics Sportsbook is 44.5.
Where can I find the latest Cardinals vs. Giants betting lines?
You can find the latest betting lines for Cardinals vs. Giants at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.