Chargers vs. Seahawks Odds, Spreads, and Lines

The Los Angeles Chargers and Seattle Seahawks will go to head-to-head in this NFL Week 4 game on Sunday afternoon. The game will kick-off at 4:25 p.m. ET, and will be played at Lumen Field.
Below, you'll find the latest Chargers vs. Seahawks odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Chargers vs. Seahawks Matchup Information
Date: Sunday, Oct. 4, 2026
Time: 4:25 p.m. ET
Location: Lumen Field, Seattle, WA
TV: CBS
Chargers vs. Seahawks Odds
Seattle is the -350 moneyline favorite against the Chargers at Fanatics Sportsbook, with Los Angeles +275 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Chargers vs. Seahawks Moneyline Odds
- Seahawks Moneyline -350
- Chargers Moneyline +275
The above odds are correct at the time of writing, see below for live odds
Chargers vs. Seahawks Spread Odds
- Chargers +7 -105
- Seahawks -7 -115
- Chargers +12.5 -210
- Seahawks -12.5 +165
- Chargers +2.5 +210
- Seahawks -2.5 -280
Chargers vs. Seahawks Over/Under Odds
- Over 43 -110
- Under 43 -110
- Over 38 -180
- Under 38 +145
- Over 48 +165
- Under 48 -210
Chargers vs. Seahawks Player Prop Odds
Jaxon Smith-Njigba is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -105. Omarion Hampton and Jadarian Price are next on the board. See the latest Justin Herbert odds and Sam Darnold odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Chargers vs. Seahawks game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Chargers vs. Seahawks Anytime Touchdown Scorer Odds
- Jaxon Smith-Njigba -105
- Omarion Hampton +110
- Jadarian Price +140
- Emanuel Wilson +215
- A.J. Barner +275
- Rashid Shaheed +290
Chargers vs. Seahawks +EV Bets
Below are the highest positive expected value bets for the Chargers vs. Seahawks game at Fanatics Sportsbook:
- Jadarian Price Under 10.5 Receiving Yards (EV 66.07%)
- Jaxon Smith-Njigba Anytime Touchdown Scorer (EV 46.23%)
- Los Angeles Chargers Moneyline (EV 31.25%)
- Los Angeles Chargers +6 Spread (EV 16.66%)
- Los Angeles Chargers +6.5 Spread (EV 16.47%)
Chargers vs. Seahawks Odds FAQs
What are the latest odds for Chargers vs. Seahawks?
The Seahawks are moneyline favorites at -350, the Chargers are moneyline outsiders at +275. The point spread line is set at 7, with the over/under total line at 43 at Fanatics Sportsbook.
Who is favored to win Chargers vs. Seahawks?
The Seahawks are favored to win against the Chargers with moneyline odds of -350, which implies a 77.78% win probability.
What is the point spread for Chargers vs. Seahawks?
The point spread for the Chargers vs. Seahawks is 7 at Fanatics Sportsbook, with Los Angeles at +7 and Seattle at -7.
What is the over/under for Chargers vs. Seahawks?
The over/under line for the Chargers vs. Seahawks at Fanatics Sportsbook is 43.
Where can I find the latest Chargers vs. Seahawks betting lines?
You can find the latest betting lines for Chargers vs. Seahawks at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.