Rams vs. Cardinals Odds, Spreads, and Lines
The Los Angeles Rams and Arizona Cardinals will go to head-to-head in this NFL Week 10 game on Sunday afternoon. The game will kick-off at 4:05 p.m. ET, and will be played at State Farm Stadium.
Below, you'll find the latest Rams vs. Cardinals odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Rams vs. Cardinals Matchup Information
Date: Sunday, Nov. 15, 2026
Time: 4:05 p.m. ET
Location: State Farm Stadium, Glendale, AZ
TV: FOX
Rams vs. Cardinals Odds
The Rams are -450 moneyline favorites against Arizona, with the Cardinals listed as +340 underdogs. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
You can also check out our guides on how to bet on the NFL and how to bet on the Super Bowl. For more betting tips and strategy, explore our moneyline betting guide, online betting guide, and how to use FanCash.
Rams vs. Cardinals Moneyline Odds
- Rams Moneyline -450
- Cardinals Moneyline +340
The above odds are correct at the time of writing, see below for live odds
Rams vs. Cardinals Spread Odds
- Rams -9.5 -110
- Cardinals +9.5 -110
- Rams -14.5 +185
- Cardinals +14.5 -240
- Rams -4.5 -210
- Cardinals +4.5 +165
Rams vs. Cardinals Over/Under Odds
- Over 40 -110
- Under 40 -110
- Over 45.5 +175
- Under 45.5 -225
- Over 35.5 -190
- Under 35.5 +150
Rams vs. Cardinals Player Prop Odds
Kyren Williams is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -170. Blake Corum and Tyler Allgeier are next on the board. See the latest Matthew Stafford odds and Jacoby Brissett odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Rams vs. Cardinals game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Rams vs. Cardinals Anytime Touchdown Scorer Odds
- Kyren Williams -170
- Blake Corum +100
- Tyler Allgeier +150
- Trey McBride +180
- Zonovan Knight +230
Rams vs. Cardinals +EV Bets
Below are the highest positive expected value bets for the Rams vs. Carinals game at Fanatics Sportsbook:
- Trey McBride Anytime Touchdown Scorer +180 (EV 13.99%)
- Los Angeles Rams -10.5 Spread +115 (EV 10.6%)
- Los Angeles Rams -8.5 Spread -115 (EV 6.66%)
- Under 39.5 Total Points -105 (EV 6.25%)
Rams vs. Cardinals Odds FAQs
What are the latest odds for Rams vs. Cardinals?
The Rams are -450 moneyline favorites at Fanatics Sportsbook, with the Cardinals available at +340. The point spread line is set at 9.5, with the over/under total line at 40 at Fanatics Sportsbook.
Who is favored to win Rams vs. Cardinals?
The Rams are available at -450 on the moneyline, which is a 81.82% win probability.
What is the point spread for Rams vs. Cardinals?
The point spread for the Rams vs. Cardinals is 9.5 at Fanatics Sportsbook, with Los Angeles at -9.5 and Arizona at +9.5.
What is the over/under for Rams vs. Cardinals?
The over/under line for the Rams vs. Cardinals at Fanatics Sportsbook is 40.
Where can I find the latest Rams vs. Cardinals betting lines?
You can find the latest betting lines for Rams vs. Cardinals at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.