Bills vs. Raiders Odds, Spreads, and Lines
The Buffalo Bills and Las Vegas Raiders will go to head-to-head in this NFL Week 6 game on Sunday afternoon. The game will kick-off at 4:25 p.m. ET, and will be played at Allegiant Stadium.
Below, you'll find the latest Bills vs. Raiders odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Bills vs. Raiders Matchup Information
Date: Sunday, Oct. 18, 2026
Time: 4:25 p.m. ET
Location: Allegiant Stadium, Paradise, NV
TV: CBS
Bills vs. Raiders Odds
Buffalo is the -260 moneyline favorite against the Raiders at Fanatics Sportsbook, with Las Vegas +210 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Bills vs. Raiders Moneyline Odds
- Bills Moneyline -260
- Raiders Moneyline +210
The above odds are correct at the time of writing, see below for live odds
Bills vs. Raiders Spread Odds
- Bills -5.5 -110
- Raiders +5.5 -110
- Bills -10.5 +190
- Raiders +10.5 -250
- Bills +0.5 -280
- Raiders -0.5 +210
Bills vs. Raiders Over/Under Odds
- Over 53 -110
- Under 53 -110
- Over 58.5 +155
- Under 58.5 -195
- Over 48.5 -190
- Under 48.5 +150
Bills vs. Raiders Player Prop Odds
Josh Allen is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -170. Ashton Jeanty and James Cook are next on the board. See the latest Josh Allen odds and Kirk Cousins odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Bills vs. Raiders game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Bills vs. Raiders Anytime Touchdown Scorer Odds
- Josh Allen -170
- Ashton Jeanty -155
- James Cook -155
- Brock Bowers +100
- D.J. Moore +150
Bills vs. Raiders +EV Bets
Below are the highest positive expected value bets for the Bills vs. Raiders game at Fanatics Sportsbook:
- Buffalo Bills -6.5 Spread (EV 14.94%)
- Buffalo Bills -4.5 Spread (EV 13.78%)
- Buffalo Bills -5.5 Spread (EV 12.75%)
Bills vs. Raiders Odds FAQs
What are the latest odds for Bills vs. Raiders?
The Bills are moneyline favorites at -260, the Raiders are moneyline outsiders at +210. The point spread line is set at 5.5, with the over/under total line at 53 at Fanatics Sportsbook.
Who is favored to win Bills vs. Raiders?
The Bills are favored to win against the Raiders with moneyline odds of -260, which implies a 72.22% win probability.
What is the point spread for Bills vs. Raiders?
The point spread for the Bills vs. Raiders is 5.5 at Fanatics Sportsbook, with Buffalo at -5.5 and Las Vegas at +5.5.
What is the over/under for Bills vs. Raiders?
The over/under line for the Bills vs. Raiders at Fanatics Sportsbook is 53.
Where can I find the latest Bills vs. Raiders betting lines?
You can find the latest betting lines for Bills vs. Raiders at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.