Chargers vs. Chiefs Odds, Spreads, and Lines
The Los Angeles Chargers and Kansas City Chiefs will go to head-to-head in this NFL Week 6 game on Sunday afternoon. The game will kick-off at 4:25 p.m. ET, and will be played at Arrowhead Stadium.
Below, you'll find the latest Chargers vs. Chiefs odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Chargers vs. Chiefs Matchup Information
Date: Sunday, Oct. 18, 2026
Time: 4:25 p.m. ET
Location: Arrowhead Stadium, Kansas City, MO
TV: CBS/Paramount
Chargers vs. Chiefs Odds
Kansas City is the -425 moneyline favorite against the Chargers at Fanatics Sportsbook, with Los Angeles +325 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Chargers vs. Chiefs Moneyline Odds
- Chargers Moneyline +325
- Chiefs Moneyline -425
The above odds are correct at the time of writing, see below for live odds
Chargers vs. Chiefs Spread Odds
- Chiefs -8 -115
- Chargers +8 -105
- Chiefs -13.5 +165
- Chargers +13.5 -210
- Chiefs -2.5 -350
- Chargers +2.5 +250
Chargers vs. Chiefs Over/Under Odds
- Over 42.5 -110
- Under 42.5 -110
- Over 47.5 +145
- Under 47.5 -180
- Over 37.5 -195
- Under 37.5 +155
Chargers vs. Chiefs Player Prop Odds
Kenneth Walker III is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -170. Travis Kelce and Xavier Worthy are next on the board. See the latest Justin Herbert odds and Patrick Mahomes odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Chargers vs. Chiefs game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Chargers vs. Chiefs Anytime Touchdown Scorer Odds
- Kenneth Walker III -170
- Travis Kelce +180
- Xavier Worthy +200
- Omarion Hampton +260
- Emmett Johnson +350
Chargers vs. Chiefs +EV Bets
Below are the highest positive expected value bets for the Chargers vs. Chiefs game at Fanatics Sportsbook:
- Omarion Hampton Anytime Touchdown Scorer (EV 31.18%)
- Kenneth Walker III Anytime Touchdown Scorer (EV 9.21%)
- Los Angeles Chargers +7 Spread (EV 8.15%)
- Los Angeles Chargers +9.5 Spread (EV 7.95%)
- Los Angeles Chargers +9 Spread (EV 7.35%)
Chargers vs. Chiefs Odds FAQs
What are the latest odds for Chargers vs. Chiefs?
The Chiefs are moneyline favorites at -425, the Chargers are moneyline outsiders at +325. The point spread line is set at 8, with the over/under total line at 42.5 at Fanatics Sportsbook.
Who is favored to win Chargers vs. Chiefs?
The Chiefs are favored to win against the Chargers with moneyline odds of -425, which implies a 80.95% win probability.
What is the point spread for Chargers vs. Chiefs?
The point spread for the Chargers vs. Chiefs is 8 at Fanatics Sportsbook, with Kansas City at -8 and Los Angeles at +8.
What is the over/under for Chargers vs. Chiefs?
The over/under line for the Chargers vs. Chiefs at Fanatics Sportsbook is 42.5.
Where can I find the latest Chargers vs. Chiefs betting lines?
You can find the latest betting lines for Chargers vs. Chiefs at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.