Colts vs. Steelers Odds, Spreads, and Lines
The Indianapolis Colts and Pittsburgh Steelers will go to head-to-head in this NFL Week 5 game on Sunday afternoon. The game will kick-off at 1:00 p.m. ET, and will be played at Acrisure Stadium.
Below, you'll find the latest Colts vs. Steelers odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Colts vs. Steelers Matchup Information
Date: Sunday, Oct. 11, 2026
Time: 1:00 p.m. ET
Location: Acrisure Stadium, Pittsburgh, PA
TV: CBS
Colts vs. Steelers Odds
Pittsburgh is the -140 moneyline favorite against the Colts at Fanatics Sportsbook, with Indianapolis +115 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Colts vs. Steelers Moneyline Odds
- Colts Moneyline +115
- Steelers Moneyline -140
The above odds are correct at the time of writing, see below for live odds
Colts vs. Steelers Spread Odds
- Colts +2.5 -110
- Steelers -2.5 -110
- Colts +7.5 -310
- Steelers -7.5 +230
- Colts -3.5 +185
- Steelers +3.5 -240
Colts vs. Steelers Over/Under Odds
- Over 44.5 -105
- Under 44.5 -115
- Over 49.5 +150
- Under 49.5 -190
- Over 39.5 -195
- Under 39.5 +155
Colts vs. Steelers Player Prop Odds
Jaylen Warren is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -250. Jonathan Taylor and Tyler Warren are next on the board. See the latest Daniel Jones odds and Aaron Rodgers odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Colts vs. Steelers game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Colts vs. Steelers Anytime Touchdown Scorer Odds
- Jaylen Warren -250
- Jonathan Taylor -170
- Tyler Warren +145
- DK Metcalf +210
Colts vs. Steelers +EV Bets
Below are the highest positive expected value bets for the Colts vs. Steelers game at Fanatics Sportsbook:
- Jonathan Taylor Anytime Touchdown Scorer (EV 32.51%)
- Indianapolis Colts +2.5 Spread (EV 15.27%)
- Indianapolis Colts +1 Spread (EV 14.06%)
Colts vs. Steelers Odds FAQs
What are the latest odds for Colts vs. Steelers?
The Steelers are moneyline favorites at -140, the Colts are moneyline outsiders at +115. The point spread line is set at 2.5, with the over/under total line at 44.5 at Fanatics Sportsbook.
Who is favored to win Colts vs. Steelers?
The Steelers are favored to win against the Colts with moneyline odds of -140, which implies a 58.33% win probability.
What is the point spread for Colts vs. Steelers?
The point spread for the Colts vs. Steelers is 2.5 at Fanatics Sportsbook, with Pittsburgh at -2.5 and Indianapolis at +2.5.
What is the over/under for Colts vs. Steelers?
The over/under line for the Colts vs. Steelers at Fanatics Sportsbook is 44.5.
Where can I find the latest Colts vs. Steelers betting lines?
You can find the latest betting lines for Colts vs. Steelers at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.