Panthers vs. Eagles Odds, Spreads, and Lines

The Carolina Panthers and Philadelphia Eagles will go to head-to-head in this NFL Week 6 game on Sunday afternoon. The game will kick-off at 1:00 p.m. ET, and will be played at Lincoln Financial Field.
Below, you'll find the latest Panthers vs. Eagles odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Panthers vs. Eagles Matchup Information
Date: Sunday, Oct. 18, 2026
Time: 1:00 p.m. ET
Location: Lincoln Financial Field, Philadelphia, PA
TV: CBS
Panthers vs. Eagles Odds
Philadelphia is the -115 moneyline favorite against the Panthers at Fanatics Sportsbook, with Carolina -105 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Panthers vs. Eagles Moneyline Odds
- Panthers Moneyline -105
- Eagles Moneyline -115
The above odds are correct at the time of writing, see below for live odds
Panthers vs. Eagles Spread Odds
- Eagles -1 -110
- Panthers +1 -110
- Eagles -6.5 +220
- Panthers +6.5 -300
- Eagles +3.5 -210
- Panthers -3.5 +165
Panthers vs. Eagles Over/Under Odds
- Over 41.5 -110
- Under 41.5 -110
- Over 46.5 +150
- Under 46.5 -190
- Over 36.5 -220
- Under 36.5 +170
Panthers vs. Eagles Player Prop Odds
Chiba Hubbard is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -125. Tetairoa McMillan and Saquon Barkley are next on the board. See the latest Bryce Young odds and Jalen Hurts odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Panthers vs. Eagles game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Panthers vs. Eagles Anytime Touchdown Scorer Odds
- Chuba Hubbard -125
- Saquon Barkley -120
- Tetairoa McMillan +145
- Dameon Pierce +150
- Jalen Hurts +150
Panthers vs. Eagles +EV Bets
Below are the highest positive expected value bets for the Panthers vs. Eagles game at Fanatics Sportsbook:
- Chuba Hubbard Anytime Touchdown Scorer (EV 37.45%)
- Carolina Panthers +1 Spread (EV 14.37%)
- Carolina Panthers +2 Spread (EV 13.57%)
- Over 43.5 Total Points (EV 12.55%)
- Carolina Panthers +0.5 Spread (EV 6.92%)
Panthers vs. Eagles Odds FAQs
What are the latest odds for Panthers vs. Eagles?
The Eagles are moneyline favorites at -115, the Panthers are moneyline outsiders at -105. The point spread line is set at 1, with the over/under total line at 41.5 at Fanatics Sportsbook.
Who is favored to win Panthers vs. Eagles?
The Eagles are favored to win against the Panthers with moneyline odds of -115, which implies a 53.49% win probability.
What is the point spread for Panthers vs. Eagles?
The point spread for the Panthers vs. Eagles is 1 at Fanatics Sportsbook, with Philadelphia at -1 and Carolina at +1.
What is the over/under for Panthers vs. Eagles?
The over/under line for the Panthers vs. Eagles at Fanatics Sportsbook is 41.5.
Where can I find the latest Panthers vs. Eagles betting lines?
You can find the latest betting lines for Panthers vs. Eagles at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.