Titans vs. Colts Odds, Spreads, and Lines
The Tennessee Titans and Indianapolis Colts will go to head-to-head in this NFL Week 6 game on Sunday afternoon. The game will kick-off at 1:00 p.m. ET, and will be played at Lucas Oil Stadium.
Below, you'll find the latest Titans vs. Colts odds, spreads and betting lines at Fanatics Sportsbook, along with betting trends and additional game information. There's a wide range of NFL betting guidance, odds, and more at Fanatics Sportsbook.
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Titans vs. Colts Matchup Information
Date: Sunday, Oct. 18, 2026
Time: 1:00 p.m. ET
Location: Lucas Oil Stadium, Indianapolis, IN
TV: FOX
Titans vs. Colts Odds
New York is the -115 moneyline favorite against the Saints at Fanatics Sportsbook, with New Orleans -105 moneyline outsiders. Fanatics Sportsbook is offering point spread markets, totals lines, and prop markets for the game.
Titans vs. Colts Moneyline Odds
- Titans Moneyline +260
- Colts Moneyline -330
The above odds are correct at the time of writing, see below for live odds
Titans vs. Colts Spread Odds
- Colts -7 -105
- Titans +7 -115
- Colts -12.5 +185
- Titans +12.5 -240
- Colts -1.5 -300
- Titans +1.5 +220
Titans vs. Colts Over/Under Odds
- Over 44 -110
- Under 44 -110
- Over 49.5 +160
- Under 49.5 -205
- Over 39.5 -195
- Under 39.5 +155
Titans vs. Colts Player Prop Odds
Jonathan Taylor is the most likely scorer in the anytime touchdown market at Fanatics Sportsbook, at odds of -230. Tyler Warren and Tony Pollard are next on the board. See the latest Cam Ward odds and Daniel Jones odds ahead of kickoff.
Fanatics Sportsbook is offering a range of additional player prop markets for the Titans vs. Colts game, including passing touchdowns, receiving yards, rushing yards, receptions, and more.
Titans vs. Colts Anytime Touchdown Scorer Odds
- Jonathan Taylor -230
- Tyler Warren +165
- Tony Pollard +190
Titans vs. Colts +EV Bets
Below are the highest positive expected value bets for the Titans vs. Colts game at Fanatics Sportsbook:
- Jonathan Taylor Anytime Touchdown Scorer (EV 17.98%)
- Tyler Warren Anytime Touchdown Scorer (EV 14.44%)
- Under 42.5 Total Points (EV 13.48%)
- Under 45.5 Total Points (EV 5.88%)
Titans vs. Colts Odds FAQs
What are the latest odds for Titans vs. Colts?
The Colts are moneyline favorites at -330, the Titans are moneyline outsiders at +260. The point spread line is set at 7, with the over/under total line at 44 at Fanatics Sportsbook.
Who is favored to win Titans vs. Colts?
The Colts are favored to win against the Titans with moneyline odds of -330, which implies a 76.74% win probability.
What is the point spread for Titans vs. Colts?
The point spread for the Titans vs. Colts is 7 at Fanatics Sportsbook, with Indianapolis at -7 and Tennessee at +7.
What is the over/under for Titans vs. Colts?
The over/under line for the Titans vs. Colts at Fanatics Sportsbook is 44.
Where can I find the latest Titans vs. Colts betting lines?
You can find the latest betting lines for Titans vs. Colts at Fanatics Sportsbook. Fanatics offers moneyline, spread, and totals markets, as well as team and player prop betting options for every NFL game in 2026.